Je vais commenté pas à pas la procédure que j'ai employé pour moi et qui fonctionne bien évidement !
Je part du principe que vous partez d'une install neuve tout comme moi, afin d'éviter des problèmes de dépendances...
yum clean all
yum update
yum upgrade
Tout est à jour et le système est propre 
Passons à l'install de Suphp en module :
yum install mod_suphp
allez dans le fichier /etc/suphp.conf et modifier comme ceci :
[global]
;Path to logfile
logfile=/var/log/httpd/suphp_log
;Loglevel
loglevel=warn
;User Apache is running as
webserver_user=apache
;Path all scripts have to be in
docroot=/var/www
;Path to chroot() to before executing script
;chroot=/mychroot
; Security options
allow_file_group_writeable=false
allow_file_others_writeable=false
allow_directory_group_writeable=false
allow_directory_others_writeable=false
;Check wheter script is within DOCUMENT_ROOT
check_vhost_docroot=true
;Send minor error messages to browser
errors_to_browser=true
;PATH environment variable
env_path=/bin:/usr/bin
;Umask to set, specify in octal notation
umask=0077
; Minimum UID
min_uid=500
; Minimum GID
min_gid=500
; Use correct permissions for mod_userdir sites
handle_userdir=true
[handlers]
;Handler for php-scripts
php5-script=php:/usr/bin/php-cgi
;Handler for CGI-scripts
x-suphp-cgi=execute:!self
et modifiez le fichier /etc/httpd/conf.d/mod_suphp.conf comme ceci :
# This is the Apache server configuration file providing suPHP support..
# It contains the configuration directives to instruct the server how to
# serve php pages while switching to the user context before rendering.
LoadModule suphp_module modules/mod_suphp.so
### Uncomment to activate mod_suphp
suPHP_AddHandler php5-script
# This option tells mod_suphp if a PHP-script requested on this server (or
# VirtualHost) should be run with the PHP-interpreter or returned to the
# browser "as it is".
suPHP_Engine on
# This option tells mod_suphp which path to pass on to the PHP-interpreter
# (by setting the PHPRC environment variable).
# Do *NOT* refer to a file but to the directory the file resists in.
#
# E.g.: If you want to use "/path/to/server/config/php.ini", use "suPHP_Config
# /path/to/server/config".
#
# If you don't use this option, PHP will use its compiled in default path.
#suPHP_ConfigPath /etc
et enfin on relance apache
et c'est fini ! :
/etc/init.d/httpd restart
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